Organic acids and derivatives
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 5 G
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It has a molecular weight of 442.50 and a chemical formula of C19H38O11. This compound appears as a colorless to light yellow liquid with a density of 1.122 g/cm3. For in vitro solubility, it dissolves in DMSO at 200 mg/mL.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: liquid
- Color: colorless to light yellow
- In vitro solubility: 200 mg/mL in DMSO
- Pure form storage: stable for 3 years at -20°C or 2 years at 4°C
- In solvent storage: stable for 6 months at -80°C or 1 month at -20°C
eMolecules 123-04-6 | 3-(Chloromethyl)heptane | Ambeed | MFCD00018940 | 148.670 | C8H17Cl | 98.000 | CCCCC(CC)CCl | 25g | 599120951
3-(Chloromethyl)heptane | Ambeed | 123-04-6 | MFCD00018940 | 148.670 | C8H17Cl | 98.000 | CCCCC(CC)CCl | 25g | 599120951
![eMolecules 6132-04-3 | Sodium citrate dihydrate, ACS reagent grade | Oakwood Chemical | MFCD00150031 | 294.098 | C6H9Na3O9 | 99.000 | O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 599151402](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502142598.JPG-250.jpg)
eMolecules 6132-04-3 | Sodium citrate dihydrate, ACS reagent grade | Oakwood Chemical | MFCD00150031 | 294.098 | C6H9Na3O9 | 99.000 | O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 599151402
Sodium citrate dihydrate, ACS reagent grade | Oakwood Chemical | 6132-04-3 | MFCD00150031 | 294.098 | C6H9Na3O9 | 99.000 | O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 599151402
Selleck Chemical LLC Zoledronic acid monohydrate S5244-1g
Zoledronic acid (Zoledronate CGP-4244) monohydrate a nitrogen-containing bisphosphonate is a potent osteoclast inhibitor which induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho
Medchemexpress LLC Arimoclomol citrate 5mg | 368860-21-3 | 5MG
Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins (HSP)[1 Arimoclomol citrate protects motor neurons by enhancing Hsp expression thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system[2 Arimoclomol citrate can be used for the study of Niemann Pick disease type C
eMolecules 60981-68-2 | Bis(diphenylphosphino)(isopropyl)amine | ChemScene427.468 | C27H27NP2 | 97.000 | CC(C)N(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1 | 100mg | 694122838
Bis(diphenylphosphino)(isopropyl)amine | ChemScene | 60981-68-2427.468 | C27H27NP2 | 97.000 | CC(C)N(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1 | 100mg | 694122838